Theodors Teknos, MD- Director Head and Neck Oncology Division, Professor
Theodoros Teknos, MD, and Quintin Pan, PhD, discovered that PKCe promotes an aggressive, metastatic phenotype in head and neck cancer. Their lab also designed a novel cancer cell-homing, PKCe-inhibitory peptide (HN1-PKCe) as a therapeutic strategy for head and neck cancer, work that culminated in an NIH grant activated during 2008. Teknos, Pan and Baiocchi, MD, PhD, also designed a phase I/II clinical trial with scientific correlates that received the top score and funding through the National Comprehensive Cancer Network; this novel HDAC inhibitor trial for patients with oropharyngeal cancer began accrual in 2009.
Pawan Kumar, PhD-Assistant Professor
Dr. Kumar’s lab investigates alterations in cancer and endothelial cell signaling, particularly as they relate to the p38-MAPK and Raf kinase pathways
Quintin Pan, PhD-Associate Professor and Research Director of the Head and Neck Oncology Program
Quintin Pan, PhD is an Associate Professor and Research Director of the Head and Neck Oncology Program at The Ohio State University, Department of Otolaryngology-Head and Neck Surgery. Dr. Pan received his PhD in pharmacology and completed a post-doctoral fellowship in cancer biology at the University of Michigan Medical School. Dr. Pan’s research is focused on understanding the genetic determinants of aggressive head and neck cancer. His laboratory is interested in identifying "druggable" genes/targets, to understand how these genes function in the context of head and neck cancer development and progression, and to design selective inhibitors against these genes as novel anti-cancer therapeutics. Dr. Pan’s work is funded through the National Cancer Institute, the American Cancer Society, and the Flight Attendant Medical Research Institute.
Mozaffarul Islam, PhD- Research Scientist
Dr. Islam is an authority on the Ras signaling pathway and the effect of RhoC on aggressive head and neck cancer behavior
Bhavna Kumar, MS- Program Director
Bhavna Kumar has published extensively on tumor biomarkers and their relation to tumor behavior.
Manchao Zhang, PhD, Senior Research Associate-B/H
Yanjun Hou, PhD, Research Associate 1-B/H
Arti Yadav, MS, Research Assistant 2-B/H
Hongpen Liu, MS, Research Assistant 2-B/H
