The Eye and Ear Institute
915 Olentangy Road; 4th Floor
Columbus, OH 43212
Phone: (614) 293-8310
Fax: (614) 293-9698
Email: subinoy.das@osumc.edu
URL: ent.osu.edu/7516.cfm
Current OSU Appointment
Assistant Professor, Otolaryngology
Certifications
| 2006 - present | Diplomat: National Board of Medical Examiners |
| 2007 - present | Diplomat: American Board of Otolaryngology |
Chapters In Books
Das, S and Yarbrough, W. 2002. Tumor Biology and Immunology of Head and Neck Cancer. In National Resident Online Study Guide, National Resident Curriculum Committee Module. Alexandria, VA: AAO-HNS.
Buchman, CA and Das, S. 2004. Chapter 29: Prevention of Acute Otitis Media During the Common Cold. In In: Advanced Therapy of Otitis Media. Hamilton, Ontario, Canada: Alper, Bluestone, Casselbrant, et al. BC Decker.
Das, S. 2005. Head and Neck. In ICU Recall 2nd Edition. Baltimore: LW&W.
Das, S. and Shockley, WW. 2006. Esophageal Disorders. In Bailey's Head and Neck Surgery/Otolaryngology. Baltimore: LW&W.
Das, S. and Senior BA. 2007. Injection and Anesthetic Techniques. In Rhinologic and Sleep Apnea Surgical Techniques. New York: Kountakis & Onerci, Springer.
Maeso, P, Das, S, and Kountakis SE. 2008. Revision Surgery for Allergic Fungal Rhinosinusitis. In Revision Endoscopic Sinus Surgery. Edited by Kountakis, Jacobs, and Gosepath. New York: Springer Verlag.
Maeso, P, Das, S, and Kountakis, SE. 2008. Revision Surgery of the Frontal Sinus. In Revision Endoscopic Sinus Surgery. Edited by Kountakis, Jacobs, and Gosepath. New York: Springer Verlag.
Watts, Tammara and Das, S. 2008. Tumor Biology and Immunology of Head and Neck Cancer. In National Resident Online Study Guide, 2nd edition; National Resident Curriculum Committee Module. Alexandria: AAO-HNS.
Continuing Education, Extension, or Other Courses Taught
Attending
2009 Cutting Edge Therapy of Chronic Rhinosinusitis. Bethesda Hospital, Genesis Health Care (Zanesville, OH)
5/2009 - present Problem Solving in Craniomaxillofacial Surgery. The Ohio State University (Columbus, OH), Problem Solving in Craniomaxillofacial Surgery, Columbus, Ohio. 50.
Continuing Education
2009 Cutting Edge Therapy of Chronic Rhinosinusitis. Springfield Regional Medical Center (Springfield, OH)
Grand Rounds
2009 Cutting Edge Therapy for Chronic Rhinosinusitis. Mansfield Hospital (Mansfield, OH)
Degrees
| 1993 | Diploma, Thomas Jefferson High School for Science and Technology |
| 1997 | B.A., University of Virginia, Echols Scholar - Interdisciplinary |
| 2001 | M.D., University of Virginia School of Medicine |
Edited Books
Associate Editor, ed. 2005. ICU Recall 2nd Ed. Baltimore, Maryland: LW&W.
Associate Editor, ed. 2008. ICU Recall 3rd Edition. Baltimore: LW&W.
Editorial Activities
Ad Hoc Reviewer
| 2008 - present | Laryngoscope. |
| 2007 - present | American Journal of Rhinology. |
| 2007 - present | Archives of Otolaryngology-Head and Neck Surgery. |
| 2007 - present | Otolaryngology-Head and Neck Surgery. |
Fellowship, Internship or Residency
| 2001 - 2002 | Internship, General Surgery, University of North Carolina School of Medicine, Chapel Hill, NC, United States. |
| 07/02 - 06/05 | Residency, Otolaryngology-Head & Neck Surgery, University of North Carolina School of Medicine, Chapel Hill, NC, United States. |
| 07/05 - 06/06 | Chief Resident, Otolaryngology-Head & Neck Surg, University of North Carolina School of Medicine, Chapel Hill, NC, United States. |
| 07/06 - 06/07 | Fellow, Advanced Rhinologic & Sinus Surgery, Medical College of Georgia, Augusta, GA, United States. |
Honors
| 1991 - 1995 | US Army Materiel Command Letters of Commendation. |
| 1993 | National Merit Scholar. ($2,000.00) |
| 1993 | Echols Scholar, University of Virginia. |
| 1997 | University of Virginia Lawn Resident. |
| 1997 | Madison House 300 Hours Volunteer Service Award. |
| 1997 | Phi Beta Kappa. University of Virginia, Charlottesville, VA, United States. |
| 1997 | 13 Society. University of Virginia, Charlottesville, VA, United States. |
| 1997 | Raven Society. University of Virginia, Charlottesville, VA, United States. |
| 1997 | American Indian Association Outstanding Student Award. |
| 1997 | Alfred Burger Award for Pre-Medical Leadership. University of Virginia, Charlottesville, VA, United States. |
| 1997 - 2001 | Edwin Pullen Full 4 yr Merit Scholar to UVA School of Medicine. ($52,000.00) |
| 1998 | Captain, Mid-Atlantic Medical School Softball Championship Team. |
| 1999 | 7 Society Recognition for Devotion to University. |
| 2000 | Raven Scholar. ($1,000.00) |
| 2001 | Bowman Scholarship – top clerkship performance. ($12,600.00) |
| 2001 | Alpha Omega Alpha. |
| 2004 | James Harrill Award. James Harrill Endowment. The Triological Society, Omaha, NE, United States. ($1,000.00) Subject: Chronic Sinusitis |
| 2006 | Alpha Epsilon Delta. |
| 2007 - 2009 | America’s Top Physicians, Consumers’ Research Council of America. |
| 2009 | 6th Extraordinary International Symposium on Recent Advances in Otitis Media Outstanding Laboratory Award. Ajou University, Suwon, Korea, Republic of. Subject: Otitis Media |
Licensure
| 2006 - present | Licensee: U.S. Drug Enforcement Administration |
| 2006 - 2009 | Medical License: State of Georgia |
| 2008 - present | Medical License: State of Ohio |
Memberships
| Member. American Medical Association |
| Member. American Rhinologic Society |
| Member. Georgia Society of Otolaryngology-Head and Neck Surgery |
| Member. North Carolina Medical Society |
| Member. Newton Fischer Society |
| Member. The Triological Society |
| Member. University of Virginia Alumni Association |
| Member. American Association of Otolaryngic Allergy |
| 2009 - present | Fellow. American College of Surgeons |
| 2009 - 2011 | Member. American Academy of Otolaryngology-Head and Neck Surgery. Patient Safety and Quality Improvement Committee |
Outreach
International Outreach with Denizli Military Hospital, Denizli, Turkey
Project Dates: 2008 - 2009
Description: Hosted Dr. Ugar Karapinar as a visiting scholar for 3 months
Peer Reviewed Journal Articles
Mikulski, HT, Das, S, and Bhat, RK. 1998. New Free Software to Assist in Radiation Accidents and Dose Calculations. Abstracts of the Annual Meeting of the Health Physics Society.
Alden, Tord D.; Pittman, Debra D.; Hankins, Gerald R.; Beres, Elisa J.; Engh, Johnathan A.; Das, Subinoy; Hudson, Sarah B.; Kerns, Kelvin M.; Kallmes, David F.; Helm, Gregory A. 1999. In vivo endochondral bone formation using a bone morphogenetic protein 2 adenoviral vector. Human Gene Therapy. Vol. 10, no. 13: 2245-2253.
Alden, TD. Beres, E, Das, S,Engh JA, Schuman T, Hankins GR, Kallmes D, and Helm, GA. 1999. Bone Morphogenetic Protein-9 Gene Therapy and Spinal Fusion. Neurosurgery. Vol. 45, no. 3. (September): 727.
Helm, Gregory A.; Alden, Tord D.; Beres, Elisa J.; Hudson, Sarah B.; Das, Subinoy; Engh, Jonathan A.; Pittman, Debra D.; Kerns, Kelvin M.; Kallmes, David F. 2000. Use of bone morphogenetic protein-9 gene therapy to induce spinal arthrodesis in the rodent. Journal of Neurosurgery. Vol. 92, no. 2 Suppl.: 191-196.
Alden, TD, Beres EJ, Laurent jS, Engh JA, Das, S, London SD, Jane JA Jr., Hudson SB, Helm, GA. 2000. The use of bone morphogenetic protein gene therapy in craniofacial bone repair. Journal of Craniofacial Surgery. Vol. 11, no. 1. (January): 24-30.
Varady, Peter; Li, Jin Zhong; Cunningham, Mary; Beres, Elisa J.; Das, Subinoy; Engh, Jonathan; Alden, Tord D.; Pittman, Debra D.; Kerns, Kelvin M.; Kallmes, David F.; Helm, Gregory A. 2001. Morphologic analysis of Bmp-9 gene therapy-induced osteogenesis. Human Gene Therapy. Vol. 12, no. 6: 697-710.
Das S. 2004. Truth and consequences of the new duty requirements: a resident's perspective. Archives Of Otolaryngology--Head & Neck Surgery. Vol. 130, no. 2. (February 1): 137.
Das S; Palmer OP; Leight WD; Surowitz JB; Pickles RJ; Randell SH; Buchman CA. 2005. Cytokine amplification by respiratory syncytial virus infection in human nasal epithelial cells. The Laryngoscope. Vol. 115, no. 5. (May 1): 764.
Das S; Buchman CA. 2005. Bilateral cochlear implantation: current concepts. Current Opinion In Otolaryngology & Head And Neck Surgery. Vol. 13, no. 5. (October 1): 290.
Das S; Kim D; Cannon TY; Ebert CS Jr; Senior BA. 2006. High-resolution computed tomography analysis of the greater palatine canal. American Journal Of Rhinology. Vol. 20, no. 6. (November 1): 603.
Das S; Becker AM; Perakis H; Prosser JD; Kountakis SE. 2007. The effects of smoking on short-term quality of life outcomes in sinus surgery. The Laryngoscope. Vol. 117, no. 12. (December 1): 2229.
Becker AM; Das S; Xia Z; Liu Z; Adam BL; Kountakis SE. 2008. Serum inflammatory protein profiles in patients with chronic rhinosinusitis undergoing sinus surgery: a preliminary analysis. American Journal Of Rhinology. Vol. 22, no. 2. (March 1): 139.
Das S; Maeso PA; Figueroa RE; Senior BA; Delgaudio JM; Sillers MJ; Schlosser RJ; Kountakis SE. 2008. The use of portable intraoperative computed tomography scanning for real-time image guidance: a pilot cadaver study. American Journal Of Rhinology. Vol. 22, no. 2. (March 1): 166.
Das S; Maeso PA; Becker AM; Prosser JD; Adam BL; Kountakis SE. 2008. Proteomics blood testing to distinguish chronic rhinosinusitis subtypes. The Laryngoscope. Vol. 118, no. 12. (December 1): 2231.
Positions
| 2006 - 2007 | Instructor, Medical College of Georgia. Augusta, GA, United States. |
| 2006 - 2008 | Attending Physician, Department of Veterans Affairs. Augusta, GA, United States. |
| 2007 - 2008 | Assistant Professor, Medical College of Georgia, Otolaryngology/HNS. Augusta, GA, United States. |
| 2008 - present | Assistant Professor and Director, Division of Sinus and Allergy, The Ohio State University College of Medicine, Department of Otolaryngology, Medicine, Otolaryngology-Head and Neck Surgery. Columbus, OH, United States. |
Presentations
Invited Presentations
Local
Das S, Presenter. 2008. Current Advances in the Management of Chronic Rhinosinusitis. Presented at Grand Rounds. Marion, OH.
Das S, Presenter. 2008. Current Advances in the Management of Chronic Rhinosinusitis. Presented at Grand Rounds. Marysville, OH.
Other Presentations
Local
Subinoy Das, Presenter. 1999. Bone Morphogenetic Protein-9 Gene Therapy and Spinal Fusion. Presented at Congress of Neurological Surgeons.
Subinoy Das, Presenter. 2003. Radical Neck Dissection. Presented at University of North Carolina OHNS Grand Rounds.
Subinoy Das, Presenter. 2004. Cytokine amplification by respiratory syncytial virus infection in human nasal epithelial cells. Presented at Triological Society Southern Section.
Das, S, Kanapkey, BK, Shores, CG, Weissler, MC, Couch ME, Shockley, WW, Poster Presenter. 2004. Treatment of Patulous Tracheoesophageal Fistula with Cymetra Injections and Upsizing with a Custom Prosthesis. Presented at AAO-HNS Annual Meeting. New York, NY. (September 19)
Das, S, Presenter. 2005. Epistaxis. Presented at University of North Carolina OHNS Grand Rounds. Chapel Hill, NC.
Das, S. Ferguson, MO., Editor. 2005. Cervical Schwannoma. Presented at Fischer Society Meeting. Chapel Hill, NC.
Subinoy Das, Editor. 2005. High Resolution CT Analysis of the Greater Palatine Canal. Presented at American Rhinologic Society Annual Meeting.
Subinoy Das, Presenter. 2005. Medicare and the Future of American Medicine. Presented at University of North Carolina OHNS Grand Rounds. Chapel Hill, NC.
Subinoy Das, Presenter. 2005. Speech Perception After Bilateral Cochlear Implantation in Adults with Two Year Implant Experience. Presented at Triological Society Southern Section.
Subinoy Das, Presenter. 2005. Verrucous Carcinoma. Surgery Grand Rounds. Presented at Wake Medical Center.
Das, S, Buss, E, (presenter) Clark MS, Pillsbury CH, Buchman CA. Pillsbury HC. 2005. Long-term effects of bilateral cochlear implantation in post-lingually deafened adults. Presented at 10th Symposium on Cochlear Implants in Children. Dallas, TX. (March 15)
Das, S, Presenter. 2006. Nasal and Paranasal Sinus Anatomy. Sleep Institute of Augusta. Augusta, GA. (October 30)
Das, S. Kountakis SE, Editor. 2006. The Above and Below Approach to the Frontal Sinus. Georgia Society of Otolaryngology-Head and Neck Surgery. Atlanta, GA. (November 17)
Das, S., Presenter. 2007. Endoscopic Sinus Surgical Outcomes in Smokers. Presented at Department of Family Medicine Grand Rounds. Medical College of Georgia. Augusta, GA. (May 25)
Das, S., Presenter. 2007. Endoscopic Sinus Surgical Outcomes in Smokers. Presented at Fifth Annual Porubsky Symposium. Augusta, GA. (June 22)
Das, S., Presenter. 2007. Pediatric Sinusitis. Presented at Department of Pediatrics Grand Rounds. Medical College of Georgia. Augusta, GA. (October 12)
Das, S., Presenter. 2007. Sinusitis Update. Presented at MCG Physician Assistant Curriculum Course. Medical College of Georgia. Augusta, GA. (October 24)
Das, S., Presenter. 2007. Cutting Edge Therapies for Allergic Fungal Sinusitis. Presented at Visiting Professor, Ohio State University Department of Otolaryngology. Columbus, OH. (November 8)
Das, S., Presenter. 2007. Allergic Fungal Sinusitis. Presented at Department of Pediatrics Grand Rounds. Medical College of Georgia. Augusta, GA. (November 16)
Iverson K, Das S, Presenter. 2008. Advances in Septal Perforation Repair. Presented at 6th Annual Porubsky Symposium. Augusta, GA, USA. [Peer Reviewed]
Das, S., Panelist. 2008. Rhinology Panel. Presented at Sixteenth Annual Dept of Otolaryngology Alumni Symposium. Columbus, OH. (June 13)
State
Subinoy Das, Editor. 2003. Perioperative Management of Atlantoaxial Instability in Down's Syndrome. Presented at University of North Carolina OHNS Grand Rounds.
Das, S, Presenter. 2006. Paranasal Sinus Anatomy and Surgical Landmarks. Presented at Dept of OHNS, Medical College of Georgia. Augusta, GA. (October 9)
Das, S, Presenter. 2007. Preventing Sinus Infections. Reynolds Plantation. Lake Oconee, GA. (February 24)
Das, S, Becker AM, Maeso PA, Kountakis SE, Presenter. 2008. Evidence-Based Medicine and Intraoperative CT Scanning. Presented at 6th Annual Porubsky Symposium. Augusta, GA. (June 6)
Regional
Subinoy Das, Editor. 2003. Respiratory Viruses and Acute Otitis Media. Presented at South Carolina and North Carolina Otolaryngology/Head and Neck Surgery Assembly.
Das, S. Becker A, Kountakis SE., Presenter. 2007. Prospective Study on the Effects of Smoking on Surgical Outcomes in Patients with Chronic Rhinosinusitis. Presented at Triological Society Combined Sections Meeting. Marco Island, FL. (February 17)
Das S, Maeso PA, Becker AM, Prosser JD, Adam BA, Kountakis SE, Presenter. 2008. Proteomics Blood Testing to Distinguish Chronic Sinusitis Subtypes. Presented at Triological Society Southern Section. Fort Myers, FL, USA. [Peer Reviewed]
Maeso PA, Das S, Prosser JD, Becker AM, Perakis H, Kountakis SE, Presenter. 2008. Presenting Signs and Demographics of Chronic Rhinosinusitis with Nasal Polyposis Subtypes. Presented at Triological Society Southern Section Meeting. Fort Myers, FL, USA. [Peer Reviewed]
Das, S, Conley, D, Kern, R, Palmer, J, Kountakis, S, Editor. 2008. Office and Intraoperative CT Imaging: Indications and Credentialing. Presented at American Rhinologic Society Breakfast Symposium. Chicago, IL. (September 20)
Das S, Khichi SS, Perakis H, Woodard T, Kountakis SE, Presenter. 2009. The Effects of Smoking on Quality of Life Outcomes Following Endoscopic Sinus Surgery: Four year followup. Presented at Triological Society Middle Section Meeting. Bonita Springs, FL, USA. [Peer Reviewed]
National
Alden, TD, Hankins GR, Engh JA, Das S, Beres EJ, Kallmes DF, Pittman, DM, Helm GA., Poster Presenter. 1999. Bone Morphogenetic Protein-9 Gene Therapy: A comparison to Bone Morphogenetic Protein-2 Gene Therapy. Presented at Keystone Symposium in Gene Therapy. Salt Lake City, UT.
Subinoy Das, Presenter. 1999. Bone Morphogenetic Protein Gene Therapy; BMP-2 versus BMP-9. Presented at The Neurological Society of the Virginias.
Alden, TD, Ko S, Polin R, Engh JA, Das, S, Hankins GR, Kao C, Chung L, Helm, GA. A, Poster Presenter. 1999. A Novel Tissue-Specific Gene Therapy for treatment of brain tumors utilizing the osteocalcin promoter. (Poster). Presented at 1999 AANS Meeting. (April)
Das, S. Leight, WD, Palmer, OP, and Weissler, MC, Poster Presenter. 2003. Intraoperative Electron Beam Radiotherapy for Advanced Head and Neck Cancer: Initial Experience. Presented at AAO-HNS Annual Meeting. Orlando, FL.
Leight WD, Das S, Palmer OP, and Weissler MC, Poster Presenter. 2003. Botulinum toxin therapy for adductor dysphonia: dose efficacy in an eleven-year experience. Presented at AAO-HNS Annual Meeting. Orlando, FL.
Palmer, OP, Das, S, Pickles, RJ, Randell SH, Buchman CA, Poster Presenter. 2003. Proinflammatory Cytokine Induction in Response to Respiratory Syncytial Virus Infection in Well-Differentiated Epithelial Cells. Presented at The Midwinter Meeting of the Association of Research in Otolaryngology. Daytona Beach, FL. (February 25)
Das, S, Leight WD, Palmer, OP, Kim HS, Buchman CA, Poster Presenter. 2003. Increased Gene Expression of Nuclear Factor Kappa-B Following RSV Infection of Well-Differentiated Human Epithelial Cells. Presented at 8th International Symposium on Recent Advances in Otitis Media. Fort Lauderdale, FL. (June 3 - 7)
Leight, WD, Das, S, Palmer, OP, Randell SH, Buchman CA, Poster Presenter. 2003. Amplification of Proinflammatory Cytokine Response by Respiratory Syncytial Virus Infection in Well Differentiated Epithelial Cells. Presented at 8th International Symposium on Recent Advances in Otitis Media. Fort Lauderdale, FL. (June 3 - 7)
Das, S. Brown CJ, Buchman, CA., Poster Presenter. 2004. Intraoperative Evoked Potentials Monitoring For Cochlear Implantation In Common Cavities. Presented at AAO-HNS Annual Meeting. New York. (September 20)
Becker A., Das S., Kountakis SE., Presenter. 2007. Correlation of Tissue Eosinophilia to Peripheral Eosinophilia and SNOT 20 Scores in Chronic Rhinosinusitis. Presented at Triological Society Combined Sections Meeting. Marco Island, FL. [Peer Reviewed]
Maeso, PA, Das, S, Kountakis, SE, Presenter. 2008. Effect of Treatment with Zileuton in Patients with Chronic Rhinosinusitis with Nasal Polyposis. Presented at American Rhinologic Society 2008 COSM Meeting. Orlando, FL. (May 1)
Maeso, PA, Prosser, JD, Das, S, Kountakis, SE, Poster Presenter. 2008. The Role of Intranasal Budesonide Irrigations in the Treatment of Chronic Hyperplastic Rhinosinusitis. Presented at Triological Society Annual Meeting. Orlando, FL. (May 1)
Das, S., Presenter. 2008. Evidence Based Medicine in Intraoperative CT Scanning. Medtronic 2008 National Sales Meeting. Scottsdale, AZ. (June 3)
Barnes, VA, Das, S, Kenny J, Walker D, Bedden DT, Kornegay D, Stevens AM, Cibirka, RM, Poster Presenter. 2008. Impact of the 'I AM FIT' Project on Blood Pressure in Teenagers. Presented at Annual International Interdisciplinary Conference on Hypertension and Related Risk Factors in Ethnic Populations. (July 18 - 20)
International
Clark, MS, Buss E, Das, S, Pillsbury HC, Pillsbury C, Buchman CA., Presenter. 2006. Review of clinical outcomes in adult bilateral cochlear implants recipients following 3 years of implantation. Presented at 9th International Conference on Cochlear Implants. Vienna, Austria. (June 14)
Das S, Jurcisek JA, McGillivary G, Bakaletz LO, Presenter. 2009. Development of a Chinchilla Model to Allow Direct, Continuous Imaging of Fluorescent Non-typeable Haemophilus Influenzae during Experimental Chronic Rhinosinusitis. Presented at Rhinoworld. Philadelphia, PA, USA. [Peer Reviewed]
Das S, McGillivary G, Jurcisek JA, Bakaletz LO, Presenter. 2009. Neutrophil-derived antimicrobial peptides are novel components of the extracellular matrix of NTHI-induced biofilms and are associated with dsDNA. Presented at 6th Extraordinary International Symposium on Recent Advances in Otitis Media. Seoul, South Korea. [Peer Reviewed]
Professional Activities
Conference Participation
| 2009 | Stryker Corporation. Presenter. Problem Solving in Craniomaxillofacial Reconstruction. Columbus, OH. |
| 2009 - present | Faculty, American Rhinologic Society Scientific Program, Rhinoworld 2009. Moderator. American Rhinologic Society. Rhinoworld. Philadelphia, PA, USA. |
Consultation
| 2008 - 2009 | Medtronic ENT Research Advisor for New Products. Industry. Medtronic ENT. Medtronic ENT Research Laboratory. Jacksonville, FL, USA. Key achievements: Assisted with the prototype development of the Medtronic Fusion Image Guidance system, which has become the #1 image guidance system used in America in ENT marketshare. |
Education
| 2006 - 2007 | Associate Director. |
| 08/2006 | Course Director. Augusta, GA. |
| 2007 | Lab. Course Director. Savannah, GA. |
| 2007 - 2008 | Co-Director. |
| 2007 - 2008 | Faculty. |
| 06/06/2007 - 06/07/2007 | Course Director. Augusta, GA. |
| 04/2009 - 06/2009 | Rhinology Curriculum. Course Director. Department of Otolaryngology-Head and Neck Surgery. Hamilton Hall. Columbus, OH, USA. Key achievements: Hosted 20 person cadaver course and symposium sponsored by Medtronic and Stryker Corporation |
Medical
| 1992 - 1997 | Contract Student Manager. |
| 1999 | Leadership in Academic Medicine Seminar instructed by Governor/Senator Lowell Weicker, University of Virginia. |
Research Interests
I currently serve as the Director of Sinus and Allergy, Department of Otolaryngology-Head and Neck Surgery and also as a Research Associate in the Center for Microbial Pathogenesis at the Research Institute, Nationwide Children's Hospital. The focus of our research mission is to develop personalized diagnostic and treatment regimens for the care of chronic rhinosinusitis (CRS). This will allow us to deliver personalized medicine to our patients and reduce the number of antibiotics prescribed for the diagnosis of sinusitis or the common cold, one of the 8 major goals of the Obama Workgroup on Healthcare Reform and a major named goal of Health People 2010. Specifically, it is now known that many patients with CRS have a greater concentration of non-typeable Haemophilus influenzae (NTHI) in the bacterial biofilms located within their sinus cavities compared to healthy patients. The specific hypothesis being tested in our research is that the presence of NTHI biofilms, which are known to be highly recalcitrant, are positively correlated with the development of CRS and that unique lipooligosaccharides and inflammatory byproducts obtained from nasopharyngeal lavage fluids and/or swabs of sinus secretions may be used as a non-invasive biomarker for CRS. These areas can be non-invasively swabbed and/or lavaged using rigid sinonasal endoscopy in the office setting. As a result, patients with symptoms of CRS specifically associated with NTHI biofilms could possibly obtain a non-invasive test in the physician’s office that would allow the clinician to make a more accurate diagnosis and objectively follow each patient’s responsiveness to customized therapy. Patients without evidence for a chronic bacterial infection, or evidence for a non-infectious cause of their chronic sinus disease maybe treated conservatively without antibiotic therapy, and instead with treatments specifically tailored to their disease. Achieving these goals would allow us to deliver more efficient care to our patients and improve quality while decreasing health care expenditures from often inappropriate and unnecessary empiric treatments.
Research selected for oral presentation at Rhinoworld, Philadelphia PA, April 2009 (International symposium held every decade)
Research selected for oral presentation at 6th Extraordinary International Symposium on Otitis Media, Seoul, South Korea, May 2009 (held every 4 years)
Funding:
Selected as OSU CCTS KL2 Scholar
Recipient of NIH/NIDCD R01 Adm Supplement to Promote Emergence of Otolaryngologist Investigators
Awards: 6th Extraordinary International Symposium on Otitis Media Research Award for Outstanding Laboratory, Seoul, South Korea, May 2009.
Develop diagnostic tests to rapidly identify patients with severe forms of sinus disease and apply intellectual property into clinical application.
Continue to compete for public and private sponsorship of research to continue scientific discovery and innovation needed to enhance the care for patients suffering from sinus disease.
Undergrad., Grad. and Prof. Courses Taught
University of Virginia, Biology. Course Director for Department of Biology Research Elective
University of North Carolina, Course Director Department of Otolaryngology Research Seminar
Spring 2009. The Ohio State University, Otolaryngology-Head and Neck Surgery. Rhinology Course Curriculum
Spring 2009. The Ohio State University, Surgery. Surgical Clerkship Lecture Series
Spring 2009. The Ohio State University, Otolaryngology-Head and Neck Surgery. Problem Solving in Craniomaxillofacial Reconstruction
